ADVANCED CLINICALS Manuka Honey Cream

ADVANCED CLINICALS Manuka Honey Cream

Efficacy100/100IrritancyHigh
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Works for

1 of 1 advertised claim delivered

Moisturizing
Paraffinum liquidum, Isopropyl myristate + 12 more
Strong evidence
What the product description says
“This Manuka Honey Body Cream, infused with Collagen, Beeswax, and Chamomile Extract, nourishes and soothes extremely dry, dehydrated skin, helping to renew softness and restore a comforted, replenished feel.”
Source: Advanced Clinicals

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, soluble collagen.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: beeswax, caprylic/capric triglyceride.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: paraffinum liquidum

Isopropyl myristateKey active· EmollientEffect: HighAn emollient that helps soften the skin. Could be comedogenic~2.8–4.1%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.5–2.2%
Paraffinum liquidumHero· Emollient, OcclusiveEffect: HighMineral oil. One of the most effective and well studied occlusive and emollient moisturizing ingredients. Helps reduce moisture loss in skin and repair skin barrier function~5.8–8.7%
Soluble collagenKey active· HumectantEffect: HighA typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin~0.5–1.15%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~1.1–1.6%
BeeswaxKey active· Emollient, OcclusiveEffect: HighForms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen~0.45–1%
Glyceryl stearate seKey activeEffect: MediumUsed to stabilize the product formulations and works as an emollient~1.7–2.5%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~3.2–4.7%
Honey extractKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin~0.55–1.35%
Aloe barbadensis leaf juice powderEffect: LowTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~0.3–0.7%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~2–3%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.15–0.55%
Camellia sinensis leaf extractEffect: LowCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.3–0.7%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.15–0.55%
Anti-oxidation
Not advertised by the brand · Camellia sinensis leaf extract, Tocopherol
Moderate evidence

This product contains antioxidants (camellia sinensis leaf extract) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

Camellia sinensis leaf extractKey activeEffect: MediumCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.3–0.7%
TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.15–0.55%

Can it cause trouble?

Irritancy
3 strong irritants: Rosa damascena flower extract, Parfum + 1 more — patch-test recommended
High risk
We flagged 13 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Anthemis nobilis flower extractA plant extract that one one hand, can contain compounds that can help calm down skin irritation, but, on the other hand, its other compounds (especially fragrant ones) can themselves be irritatingHigh~0.3–0.75%est.
Rosa damascena flower extractUsed as a fragrance. Can be irritatingHigh~0.2–0.7%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.15–0.65%est.
Iodopropynyl butylcarbamateA preservative. Can be irritatingHigh~0.01–0.02%est.
Ceteareth-20Helps oil and water mix together. Has some emollient propertiesMedium~1.3–1.9%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~1.1–1.6%est.
Honey extractHelps attract water to the upper layer of the skinMedium~0.55–1.35%est.
Aloe barbadensis leaf juice powderTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skinMedium~0.3–0.7%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.15–0.55%est.
Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.1–0.45%est.
1,2-hexanediolA preservativeMedium~0.05–0.25%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.05–0.2%est.
Sodium citrateHelps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve productsMedium~0.01–0.1%est.
Comedogenic
4 ingredients rated 2 or more on the 0–5 pore-clogging scale
4 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Isopropyl myristateAn emollient that helps soften the skin. Could be comedogenic3/5~2.8–4.1%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~3.2–4.7%est.
Glyceryl stearate seUsed to stabilize the product formulations and works as an emollient2/5~1.7–2.5%est.
Ceteareth-20Helps oil and water mix together. Has some emollient properties2/5~1.3–1.9%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Paraffinum liquidum~5.8–8.7%
Hero · Moisturizing
Irritation risk
Low
Works for
Moisturizing

Mineral oil. One of the most effective and well studied occlusive and emollient moisturizing ingredients. Helps reduce moisture loss in skin and repair skin barrier function

More about Paraffinum liquidum
Cetearyl alcohol~3.2–4.7%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Isopropyl myristate~2.8–4.1%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

An emollient that helps soften the skin. Could be comedogenic

More about Isopropyl myristate
Butylene glycol~2–3%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Glyceryl stearate se~1.7–2.5%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

Used to stabilize the product formulations and works as an emollient

More about Glyceryl stearate se
Glycerin~1.5–2.2%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Ceteareth-20~1.3–1.9%
Comedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Cleansing

Helps oil and water mix together. Has some emollient properties

More about Ceteareth-20
Caprylic/capric triglyceride~1.1–1.6%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Honey extract~0.55–1.35%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps attract water to the upper layer of the skin

More about Honey extract
Soluble collagen~0.5–1.15%
Key active
Irritation risk
Low
Works for
Moisturizing

A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin

More about Soluble collagen
Beeswax~0.45–1%
Key active
Irritation risk
Low
Works for
Moisturizing

Forms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen

More about Beeswax
Anthemis nobilis flower extract~0.3–0.75%
Irritant · high
Irritation risk
High
Works for
Reduces irritationAnti-inflammatory

A plant extract that one one hand, can contain compounds that can help calm down skin irritation, but, on the other hand, its other compounds (especially fragrant ones) can themselves be irritating

More about Anthemis nobilis flower extract
Aloe barbadensis leaf juice powder~0.3–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin

More about Aloe barbadensis leaf juice powder
Camellia sinensis leaf extract~0.3–0.7%
Key active
Irritation risk
Low
Works for
AntibacterialAnti-oxidationAnti-agingMoisturizingEvens skin toneAnti-blemish

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract
Rosa damascena flower extract~0.2–0.7%
Irritant · high
Irritation risk
High

Used as a fragrance. Can be irritating

More about Rosa damascena flower extract
Parfum~0.15–0.65%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Phenoxyethanol~0.2–0.7%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Tocopherol~0.15–0.55%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-agingMoisturizingAnti-inflammatory

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Caprylyl glycol~0.15–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Acrylates/c10-30 alkyl acrylate crosspolymer~0.1–0.45%
Irritant · medium
Irritation risk
Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer
Tetrasodium glutamate diacetate~0.1–0.35%
Formula
Irritation risk
Low

Helps stabilize the product formulation

More about Tetrasodium glutamate diacetate
Sodium hydroxide~0.1–0.35%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Iodopropynyl butylcarbamate~0.01–0.02%
Irritant · high
Irritation risk
High

A preservative. Can be irritating

More about Iodopropynyl butylcarbamate
1,2-hexanediol~0.05–0.25%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Citric acid~0.05–0.2%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Sodium citrate~0.01–0.1%
Irritant · medium
Irritation risk
Medium

Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products

More about Sodium citrate
Sodium benzoate~0.05–0.15%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Ingredient list view

Water, Paraffinum liquidum, Cetearyl alcohol, Isopropyl myristate, Butylene glycol, Glyceryl stearate se, Glycerin, Ceteareth-20, Caprylic/capric triglyceride, Honey extract, Soluble collagen, Beeswax, Anthemis nobilis flower extract, Aloe barbadensis leaf juice powder, Camellia sinensis leaf extract, Rosa damascena flower extract, Parfum, Phenoxyethanol, Tocopherol, Caprylyl glycol, Acrylates/c10-30 alkyl acrylate crosspolymer, Tetrasodium glutamate diacetate, Sodium hydroxide, Iodopropynyl butylcarbamate, 1,2-hexanediol, Citric acid, Sodium citrate, Sodium benzoate

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Advanced Clinicals
$15.99
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Amazon USPrice as of 10/23/2026 21:29 GMT
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
ADVANCED CLINICALSManuka Honey CreamYOUR PRODUCTElastaliftHyaluronic Acid Face & Body Cream MoisturizerBiodermaAtoderm NutritiveAvèneXeracalm A.D Creme Repilidante
Match—62%61%60%
Price$15.99$15.99$20.01+$4.02—
Shared key ingredients—4 of 73 of 73 of 7
Key difference—Ceramide 2Cera MicrocristallinaArginine
Irritancy High Medium Low Low
Drying alcohol————
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Product summary

Judging from the ingredient list, "ADVANCED CLINICALS - Manuka Honey Cream" works well for improving skin hydration The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Glycerin, hydrolyzed collagen, honey extract, royal jelly extract and butylene glycol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Paraffinum liquidum, hydrolyzed collagen, isopropyl myristate, beeswax and cetearyl alcohol in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Irritation risk

This formulation includes some common irritants, including ingredients that do not provide a benefit for the skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails at around 15.00$ in the United States and for 186.91A$ in Australia.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 6 studies and safety reviews.

  1. 1
  2. 2
  3. 3
    Vitamin E in dermatologyncbi.nlm.nih.gov
  4. 4
    Vitamin E and Skin Healthlpi.oregonstate.edu
  5. 5
  6. 6

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