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ADVANCED CLINICALS Hemp Seed Oil
ADVANCED CLINICALS

ADVANCED CLINICALS Hemp Seed Oil

Efficacy58/100IrritancyHigh
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Works for

1 of 3 advertised claims delivered

Moisturizing
7 ingredients credited for this claim
Good support
What the product description says
“Quantity DescriptionThe perfect anti-aging, soothing moisturizer, and it comes straight from nature.”
Source: Advanced Clinicals

This product can help soften the skin and reduce its moisture loss with emollients and occlusives: caprylic/capric triglyceride, squalene.

Keep in mind that this product does not contain effective ingredients to attract water to the upper layer of the skin. This is why an additional product with humectants like glycerin or hyaluronic acid can be helpful (apply it before this product for the best results).

SqualeneKey active· Emollient, OcclusiveEffect: HighAn oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast~4.8–7.2%
Cannabis sativa seed oilKey active· EmollientEffect: HighA plant oil that due to its high linoleic acid content can help strengthen skin's barrier function and soften its upper layer~5.5–8.2%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~23–34%
Helianthus annuus extractKey active· EmollientEffect: HighHelps soften the upper layer of the skin~2.3–3.4%
Centella asiatica extractUnder-dosedEffect: HighA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.15–0.7%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.2–1.8%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.4–0.9%
Anti-aging
3 ingredients credited for this claim
Limited support
What the product description says
“Quantity DescriptionThe perfect anti-aging, soothing moisturizer, and it comes straight from nature.”
Source: Advanced Clinicals

This product does not contain ingredients that are able to reduce fine lines and wrinkles or help with skin elasticity, but it can improve the look of the skin temporarily through moisturization. Well-moisturized skin might also be able to repair the sun damage better.

This ingredient squalene might be able to help neutralize free radicals in skin and help it fight off some of the sun damage.

Centella asiatica extractUnder-dosedEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.15–0.7%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.4–0.9%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.2–1.8%
Anti-blemish
3 ingredients credited for this claim
Limited support
What the product description says
“Provides long lasting moisture while balancing oily skin to ensure your pores won’t get clogged.”
Source: Advanced Clinicals

This product contains ingredients (rosmarinus officinalis leaf extract) that could help reduce blemishes and clogged pores in theory, but there is not enough evidence that they actually work.

Rosmarinus officinalis leaf extractKey activeEffect: MediumCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating~2.3–3.5%
Centella asiatica extractEffect: Low, below effective doseA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.15–0.7%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.4–0.9%
Anti-oxidation
Not advertised by the brand · 5 ingredients credited for this claim
Moderate support

This product contains antioxidants (squalene) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

SqualeneKey activeEffect: MediumAn oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast~4.8–7.2%
Rosmarinus officinalis leaf extractEffect: LowCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating~2.3–3.5%
TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.2–1.8%
Camellia sinensis leaf extractUnder-dosedEffect: MediumCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.4–0.9%
Centella asiatica extractUnder-dosedEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.15–0.7%

Can it cause trouble?

Irritancy
4 strong irritants: Rosmarinus officinalis leaf extract, Rosa damascena flower extract + 2 more — patch-test recommended
High risk
We flagged 7 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Rosmarinus officinalis leaf extractCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritatingHigh~2.3–3.5%est.
Rosa damascena flower extractUsed as a fragrance. Can be irritatingHigh~0.95–1.4%est.
Arnica montana flower extractA plant extract that can be irritating. It can have some anti-bacterial properties, but there are no evidence of a beneficial effect for skinHigh~0.55–1.3%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.05–0.2%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~23–34%est.
Cannabis sativa seed oilA plant oil that due to its high linoleic acid content can help strengthen skin's barrier function and soften its upper layerMedium~5.5–8.2%est.
Centella asiatica extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.Medium~0.15–0.7%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
SqualeneAn oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast2/5~4.8–7.2%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Caprylic/capric triglyceride~23–34%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Cannabis sativa seed oil~5.5–8.2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A plant oil that due to its high linoleic acid content can help strengthen skin's barrier function and soften its upper layer

More about Cannabis sativa seed oil
Squalene~4.8–7.2%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
MoisturizingAnti-oxidation

An oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast

More about Squalene
Oryza sativa bran extract~3.8–5.7%
Formula
Irritation risk
Low

Used to thicken the product consistency

More about Oryza sativa bran extract
Rosmarinus officinalis leaf extract~2.3–3.5%
Key activeIrritant · high
Irritation risk
High
Works for
Anti-blemishAnti-oxidationAntibacterial

Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating

More about Rosmarinus officinalis leaf extract
Helianthus annuus extract~2.3–3.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Helianthus annuus extract
Tocopherol~1.2–1.8%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-agingAnti-inflammatory

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Rosa damascena flower extract~0.95–1.4%
Irritant · high
Irritation risk
High

Used as a fragrance. Can be irritating

More about Rosa damascena flower extract
Arnica montana flower extract~0.55–1.3%
Irritant · high
Irritation risk
High

A plant extract that can be irritating. It can have some anti-bacterial properties, but there are no evidence of a beneficial effect for skin

More about Arnica montana flower extract
Camellia sinensis leaf extract~0.4–0.9%
Under-dosed
Irritation risk
Low
Works for
AntibacterialAnti-oxidationAnti-agingEvens skin toneMoisturizingAnti-blemish

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract
Centella asiatica extract~0.15–0.7%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Reduces rednessAnti-inflammatoryMoisturizingReduces irritationAnti-oxidationAnti-agingAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.

More about Centella asiatica extract
Silica dimethyl silylate~0.3–0.75%
Formula
Irritation risk
Low

Used to create a thicker product consistency

More about Silica dimethyl silylate
Silica~0.2–0.75%
Formula
Irritation risk
Low

Used to absorb oil and can temporarily mattify skin

More about Silica
Parfum~0.05–0.2%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Ingredient list view

Caprylic/capric triglyceride, Cannabis sativa seed oil, Squalene, Oryza sativa bran extract, Rosmarinus officinalis leaf extract, Helianthus annuus extract, Tocopherol, Rosa damascena flower extract, Arnica montana flower extract, Camellia sinensis leaf extract, Centella asiatica extract, Silica dimethyl silylate, Silica, Parfum

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Amazon USPrice as of 10/17/2026 18:20 GMT
$9.99
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Advanced Clinicals
$12.95
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 21 studies and safety reviews.

  1. 1
    Hemp (Cannabis sativa L.) seed oil: Analytical and phytochemical characterization of unsaponifiable fractionpubs.acs.org
  2. 2
    Hemp (Cannabis sativa L.) as a Resource for Green Cosmeticstandfonline.com
  3. 3
    Squalene and its potential clinical useseuropepmc.org
  4. 4
    Biological and Pharmacological Activities of Squalene and Related Compounds: Potential Uses in Cosmetic Dermatology mdpi.com
  5. 5
    Enhanced comedo formation in rabbit ear skin by squalene and oleic acid peroxidesonlinelibrary.wiley.com
  6. 6
    Allergic contact dermatitis induced by rosemary leaf extract in a cleansing gelpubmed.ncbi.nlm.nih.gov
ADVANCED CLINICALS Hemp Seed Oil
ADVANCED CLINICALSHemp Seed Oil
Buy at Advanced Clinicals$12.95$9.99as of 10/17 18:20 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy at Advanced Clinicals$12.95$9.99as of 10/17 18:20 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.