You can use this product either in the morning or at night, before your moisturizer or sunscreen. You can use it daily, but, in case you notice signs of irritation, reducing the application to every other night might help.

Use every day, as many times as needed. For most people, it's best to use a moisturizer twice per day. In the morning, apply it before your sunscreen (or skip the moisturizer in the morning if your sunscreen feels hydrating enough). In the evening, a moisturizer is usually the last step of a routine.