You can use this product either in the morning or at night, before your moisturizer or sunscreen. You can use it daily, but, in case you notice signs of irritation, reducing the application to every other night might help.

Start slowly with this product: it can be irritating, but your skin can adjust to it with time. It is best to start using this product only a few times a week or every other day for the first few weeks. Mild dryness is normal when starting using a retinoid. Once your skin is able to tolerate the product well, you can slowly increase the frequency of use to every day. Make sure to apply a moisturizer regularly when using this product. Apply this product on clean skin, before a moisturizer. Most people prefer using this product at night, but it can be used in the morning as well (once per day in total).