There is no exact dupe for iS Clinical Tri-Active Exfoliant. The nearest formula is Obagi CLENZIderm M.D. Therapeutic Lotion (55% match), which shares the original's only key ingredient (Benzoyl peroxide).
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
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Note: Ingredient concentrations are estimated; products aren't lab-tested. A close match doesn't guarantee the same feel.