Avène Cicalfate Cream

Avène Cicalfate Cream

Efficacy100/100IrritancyLow
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Works for

1 of 1 advertised claim delivered

Moisturizing
Paraffinum liquidum, Arginine + 7 more
Strong evidence
What the product description says
“Cicalfate Cream”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: arginine, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, beeswax.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: paraffinum liquidum

ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.55–0.85%
BeeswaxKey active· Emollient, OcclusiveEffect: HighForms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen~0.6–0.9%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~7.5–9.2%
Cera albaKey active· Emollient, OcclusiveEffect: HighForms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen~0.55–0.85%
Cera microcristallinaKey active· Emollient, OcclusiveEffect: HighHelps to soften the upper layer of the skin, reduce water loss from its surface and create a thicker product consistency~0.2–0.35%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.1–3.8%
Paraffinum liquidumHero· Emollient, OcclusiveEffect: HighMineral oil. One of the most effective and well studied occlusive and emollient moisturizing ingredients. Helps reduce moisture loss in skin and repair skin barrier function~4.6–5.6%
Hydrogenated vegetable oilKey active· EmollientEffect: MediumAn oil from a mixture of different vegetables. Helps soften the upper layer of the skin~2.4–3%
Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~1.6–2%

Can it cause trouble?

Irritancy
5 flagged ingredients
Low risk
We flag 5 ingredients with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.
IngredientFunctionIrritationEst. amount
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~1.6–2%est.
Zinc sulfateA preservative. It can be irritatingHigh~0.15–0.3%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~7.5–9.2%est.
Aluminum stearateUsed to help evenly disperse other ingredients (for example, pigment) in a formulationMedium~0.95–1.2%est.
Cera albaForms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergenMedium~0.55–0.85%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Hydrogenated vegetable oilAn oil from a mixture of different vegetables. Helps soften the upper layer of the skin2/5~2.4–3%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Caprylic/capric triglyceride~7.5–9.2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Paraffinum liquidum~4.6–5.6%
Hero · Moisturizing
Irritation risk
Low
Works for
Moisturizing

Mineral oil. One of the most effective and well studied occlusive and emollient moisturizing ingredients. Helps reduce moisture loss in skin and repair skin barrier function

More about Paraffinum liquidum
Glycerin~3.1–3.8%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Hydrogenated vegetable oil~2.4–3%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
Moisturizing

An oil from a mixture of different vegetables. Helps soften the upper layer of the skin

More about Hydrogenated vegetable oil
Zinc oxide~2.7–3.4%
Formula
Irritation risk
Low
Works for
Sun protection

A broad spectrum sunblock (protects from both UVA and UVB rays). Is suitable for most sensitive skins. In small concentrations, can be used as a colorant

More about Zinc oxide
Propylene glycol~1.6–2%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Polyglyceryl-2 sesquiisostearate~1.4–1.7%
Formula
Irritation risk
Low
Works for
Cleansing
More about Polyglyceryl-2 sesquiisostearate
Peg-22/dodecyl glycol copolymer~1.2–1.4%
Formula
Irritation risk
Low
Works for
Cleansing
More about Peg-22/dodecyl glycol copolymer
Aluminum stearate~0.95–1.2%
Irritant · medium
Irritation risk
Medium

Used to help evenly disperse other ingredients (for example, pigment) in a formulation

More about Aluminum stearate
Aquaphilus dolomiae ferment filtrate~0.7–1.1%
Formula
Arginine~0.55–0.85%
Key active
Irritation risk
Low
Works for
Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine
Beeswax~0.6–0.9%
Key active
Irritation risk
Low
Works for
Moisturizing

Forms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen

More about Beeswax
Cera alba~0.55–0.85%
Key activeIrritant · medium
Irritation risk
Medium
Works for
CleansingMoisturizing

Forms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen

More about Cera alba
Copper sulfate~0.35–0.6%
Formula
Irritation risk
Low
More about Copper sulfate
Magnesium stearate~0.3–0.55%
Formula
Irritation risk
Low

Used to create a nice product texture

More about Magnesium stearate
Magnesium sulfate~0.25–0.45%
Formula
Irritation risk
Low

Used to create a thicker product consistency

More about Magnesium sulfate
Microcrystalline wax~0.2–0.35%
Formula
Irritation risk
Low

Used to create a thicker product consistency

More about Microcrystalline wax
Cera microcristallina~0.2–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to soften the upper layer of the skin, reduce water loss from its surface and create a thicker product consistency

More about Cera microcristallina
Tromethamine~0.1–0.2%
Formula
Irritation risk
Low

Helps adjust pH in products

More about Tromethamine
Zinc sulfate~0.15–0.3%
Irritant · high
Irritation risk
High

A preservative. It can be irritating

More about Zinc sulfate
Ingredient list view

Water, Caprylic/capric triglyceride, Paraffinum liquidum, Glycerin, Hydrogenated vegetable oil, Zinc oxide, Propylene glycol, Polyglyceryl-2 sesquiisostearate, Peg-22/dodecyl glycol copolymer, Aluminum stearate, Aquaphilus dolomiae ferment filtrate, Arginine, Beeswax, Cera alba, Copper sulfate, Magnesium stearate, Magnesium sulfate, Microcrystalline wax, Cera microcristallina, Tromethamine, Zinc sulfate

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Amazon USPrice as of 10/12/2026 12:57 GMT
$26.00
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Amazon USPrice as of 10/12/2026 12:13 GMT
$40.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
AvèneCicalfate CreamYOUR PRODUCTBootsIngredients Glycolic Body Cream
Match—52%
Price$16.80$8.02−$8.78
Shared key ingredients—2 of 8
Key difference—Glycolic Acid
Irritancy Low Low
Drying alcohol——
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Product summary

"Avène - Cicalfate Cream" is a well-rounded moisturizing product. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (arginine, glycerin and propylene glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Paraffinum liquidum, arginine, beeswax, caprylic/capric triglyceride and cera alba in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Irritation risk

There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be low. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 15.45A$ in Australia, for 15.99£ in the United Kingdom and for 28.00$ in the United States.

For a detailed price comparison: click here.

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As an Amazon Associate, WIMJ earns from qualifying purchases.