PRODUCT REVIEW

Darphin Predermine Sculpting Night Cream

Works for:

based on ingredients and %

Moisturizing
Anti-aging
Evens skin tone

Can it cause trouble?

Key actives

Yeast extract 0.25% - 0.45%Acetyl glucosamine 0.25% - 0.45%

See all ingredients

Buy from Amazon US $77.49

Price as of 3/31/2023 3:58 GMT. More info

More options from: $77.49

Add to Compare

Submit an edit

Cheaper alternatives

Clinique - Smart Clinical Repair™ Wrinkle Correcting Rich Cream

Price: $66.75

Find out more

SWANICOCO - Peptine Biome Eye Cream

Price: $18

Find out more

Product summary

"Darphin - Predermine Sculpting Night Cream" has a good moisturizing formula. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Humectants in this product (acetyl glucosamine, acetyl hexapeptide-8, diglycerin, faex and glycerin) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, oryza sativa bran oil, theobroma cacao seed butter and butyrospermum parkii butter in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

We like that this moisturizer contains peptides (palmitoyl hexapeptide-12 0.25% - 0.45%, acetyl hexapeptide-8 0.25% - 0.45%, palmitoyl tripeptide-5 0.25% - 0.45%, palmitoyl tripeptide-1 0.30% - 0.55% and palmitoyl tetrapeptide-7 0.30% - 0.55%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.

This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e, tetrahexyldecyl ascorbate and yeast extract

Irritation risk

There are quite a few common irritants in this product, including ingredients without particular skin benefits. We would not recommend it for sensitive skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 57.15£ up to 105.00£ in the United Kingdom, for 190.43A$ in Australia and for 77.49$ in the United States.

For a detailed price comparison: click here.

What can the product work for?

Anti-aging

What does the product description say?

Lift and define the facial contours with Darphin Predermine Sculpting Night Cream , a nourishing formula with noticeable anti-ageing benefits.

Source: Lookfantastic US

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains acetyl glucosamine, palmitoyl hexapeptide-12.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

acetyl glucosamine 0.25% - 0.45%

Irritation risk:

Concentration: Effectiveness: HIGH

An effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin

palmitoyl hexapeptide-12 0.25% - 0.45%

Irritation risk:

Concentration: Effectiveness: HIGH

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

palmitoyl tripeptide-1 0.3% - 0.55%

Irritation risk:

Concentration: Effectiveness: MEDIUM

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

Moisturizing

What does the product description say?

Predermine Sculpting Night Cream

Source: From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: diglycerin, faex.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, chondrus crispus extract.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl glucosamine, acetyl hexapeptide-8, palmitoyl hexapeptide-12, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5

diglycerin 0.3% - 0.55%

Irritation risk:

Concentration: Effectiveness: HIGH

Helps attract water to the upper layer of the skin

faex 0.25% - 0.45%

Irritation risk:

Concentration: Effectiveness: HIGH

Yeast extract. Helps to attract water to the upper layer of the skin

gelidiella acerosa extract 0.25% - 0.45%

Irritation risk:

Concentration: Effectiveness: HIGH

An algae extract that can help attract water to the upper layer of the skin and have some anti-oxidant properties

Evens skin tone

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: acetyl glucosamine

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: glycine soja protein.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

acetyl glucosamine 0.25% - 0.45%

Irritation risk:

Concentration: Effectiveness: HIGH

An effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin

glycine soja protein 0.3% - 0.55%

Irritation risk:

Concentration: Effectiveness: LOW

A plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking

tetrahexyldecyl ascorbate 0.25% - 0.5%

Irritation risk:

Concentration: Insufficient!

Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.

Honesty check

Buy now

Can it cause trouble?

User reviews (0)

Ingredients & concentrations

All ingredients

Key Actives

yeast extract 0.25% - 0.45%

Irritation risk:

Works for: Moisturizing, Anti-inflammatory, Reduces irritation, Anti-oxidation, Evens skin tone

Helps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin

acetyl glucosamine 0.25% - 0.45%

Irritation risk:

Works for: Moisturizing, Evens skin tone, Anti-aging, Exfoliation

An effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin

Search top rated products by actives

Potential irritants

hibiscus sabdariffa flower extract 0.25% - 0.5%

Irritation risk:

Works for: Anti-oxidation

A plant extract that can be irritating. It might contain a compound anthocyanin that could be helpful in neutralizing free radicals

gelidiella acerosa extract 0.25% - 0.45%

Irritation risk:

Works for: Moisturizing, Anti-oxidation

An algae extract that can help attract water to the upper layer of the skin and have some anti-oxidant properties

Comodogenic ingredients

butyrospermum parkii butter 5.3% - 6.5%

Irritation risk: Comedogenicity: High

Works for: Moisturizing, Anti-aging, Anti-oxidation

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

theobroma cacao seed butter 1.4% - 1.8%

Irritation risk: Comedogenicity: High

Works for: Moisturizing, Anti-oxidation, Anti-dandruff

Helps soften the upper layer of the skin and can be helpful in restoring the skin barrier function. Might have some anti-oxidant effect

All ingredients

water 45% - 55%

Irritation risk:

Plain old water

butyrospermum parkii butter 5.3% - 6.5%

Irritation risk: Comedogenicity: High

Works for: Moisturizing, Anti-aging, Anti-oxidation

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

butylene glycol 4.3% - 5.3%

Irritation risk:

Works for: Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

Ingredient list view

Water, Butyrospermum parkii butter, Butylene glycol, Simmondsia chinensis seed oil, Oryza sativa bran oil, Glyceryl stearate, Peg-100 stearate, Theobroma cacao seed butter, Propanediol, Hydrogenated vegetable oil, Tridecyl trimellitate, Squalane, Tribehenin, Polyglyceryl-3 methylglucose distearate, Triisostearin, Glycerin, Cetearyl olivate, Cetyl alcohol, Diglycerin, Menyanthes trifoliata leaf extract, Hibiscus sabdariffa flower extract, Hordeum vulgare extract, Prunus amygdalus dulcis seed extract, Gelidiella acerosa extract, Hypnea musciformis extract, Equisetum arvense extract, Cucumis sativus fruit extract, Iris pallida root extract, Palmitoyl tetrapeptide-7, Iris florentina root extract, Propylene glycol, Unknown, Acetyl glucosamine, Caffeine, Glucose, Palmitoyl tripeptide-1, Palmitoyl tripeptide-5, Oryza sativa bran extract, Acetyl hexapeptide-8, Ethylhexylglycerin, Polianthes tuberosa polysaccharide, Chondrus crispus extract, Faex, Yeast extract, Propylene glycol dicaprate, Palmitoyl hexapeptide-12, Sorbitan olivate, Glycine soja protein, Sodium hyaluronate, Tocopheryl acetate, Ethylhexyl palmitate, Helianthus annuus seed extract, Glyceryl polymethacrylate, Potassium cetyl phosphate, Caprylyl glycol, Parfum, Carbomer, Cellulose gum, Polysorbate 20, Phytic acid, Peg-8, Tetrahexyldecyl ascorbate, Hexylene glycol, Sodium hydroxide, Peg-40 hydrogenated castor oil, Ethylhexyl methoxycinnamate, Butyl methoxydibenzoylmethane, Ethylhexyl salicylate, Xanthan gum, Silica dimethyl silylate, Hexyl cinnamal, Benzyl salicylate, Alpha-isomethyl ionone, Hydroxycitronellal, Citronellol, Linalool, Amyl cinnamal, Limonene, Geraniol, Citral, Coumarin, Calcium chloride, Tetrasodium edta, Bht, Disodium edta, Tocopherol, Phenoxyethanol, Potassium sorbate, Ci 14700, Unknown, Ci 60730

	Darphin - Predermine Sculpting Night Cream	Clinique - Smart Clinical Repair™ Wrinkle Correcting Rich Cream	SWANICOCO - Peptine Biome Eye Cream	Peter Thomas Roth - Peptide 21 Wrinkle Resist Eye Cream	Eyenlip - Salmon & Peptide Nutrition Cream	Naturium - Multi-Peptide Eye Cream	DEWYCEL - Eye Plus Cream	AHC - Hydrating Essential Real Eye Cream for Face	NEOGEN X SUR.MEDIC - V.Biome Advanced Eye Cream	KLAVUU - Rejuve Pearlsation Multi Pearl Peptide Cream	ROUND LAB - Birch Juice Moisturizing Sun Stick
Price
WIMJ similarity score		46%	42%	42%	40%	40%	38%	37%	37%	37%	36%
Key ingredients	palmitoyl hexapeptide-12 palmitoyl tetrapeptide-7 +21 more	Common: palmitoyl tetrapeptide-7 palmitoyl tripeptide-1 +7 more Other: acetyl octapeptide-3 aminopropyl ascorbyl phosphate +8 more	Common: acetyl hexapeptide-8 palmitoyl tripeptide-5 +5 more Other: acetyl dipeptide-1 cetyl ester acetyl octapeptide-3 +29 more	Common: acetyl hexapeptide-8 palmitoyl hexapeptide-12 +5 more Other: tripeptide-1 hexapeptide-11 +19 more	Common: palmitoyl tetrapeptide-7 palmitoyl tripeptide-1 +5 more Other: copper tripeptide-1 niacinamide +11 more	Common: acetyl hexapeptide-8 palmitoyl tetrapeptide-7 +6 more Other: panthenol pantolactone +1 more	Common: palmitoyl tetrapeptide-7 palmitoyl tripeptide-1 +7 more Other: niacinamide adenosine +8 more	Common: acetyl hexapeptide-8 palmitoyl hexapeptide-12 +6 more Other: copper tripeptide-1 acetyl dipeptide-1 cetyl ester +45 more	Common: acetyl hexapeptide-8 palmitoyl tetrapeptide-7 +6 more Other: copper tripeptide-1 hexapeptide-11 +23 more	Common: palmitoyl tetrapeptide-7 acetyl hexapeptide-8 +3 more Other: niacinamide acetyl dipeptide-1 cetyl ester +28 more	Common: acetyl hexapeptide-8 palmitoyl hexapeptide-12 +6 more Other: niacinamide nonapeptide-1 +17 more
Irritancy	IRRITANCY HIGH	IRRITANCY MEDIUM	IRRITANCY MEDIUM	IRRITANCY MEDIUM	IRRITANCY MEDIUM	IRRITANCY MEDIUM	IRRITANCY MEDIUM	IRRITANCY HIGH	IRRITANCY MEDIUM	IRRITANCY MEDIUM	IRRITANCY MEDIUM
Potential Irritants	coumarin Has skin benefit? citral Has skin benefit? +38 more	potassium sorbate Has skin benefit? sodium dehydroacetate Has skin benefit? +15 more	parfum Has skin benefit? portulaca oleracea extract Has skin benefit? +7 more	phenethyl alcohol Has skin benefit? decyl glucoside Has skin benefit? +12 more	parfum Has skin benefit? ci 15985 Has skin benefit? +10 more	potassium sorbate Has skin benefit? ethylhexylglycerin Has skin benefit? +11 more	parfum Has skin benefit? disodium edta Has skin benefit? +12 more	benzyl benzoate Has skin benefit? retinol Has skin benefit? +41 more	citrus aurantium amara flower extract Has skin benefit? ascorbic acid Has skin benefit? +20 more	curcuma longa root extract Has skin benefit? ocimum sanctum leaf extract Has skin benefit? +20 more	ascorbic acid Has skin benefit? ulmus davidiana root extract Has skin benefit? +11 more
All ingredients	water Has skin benefit? butyrospermum parkii butter Has skin benefit? +89 more	water Has skin benefit? butyrospermum parkii butter Has skin benefit? +48 more	lactobacillus ferment Has skin benefit? water Has skin benefit? +76 more	water Has skin benefit? isononyl isononanoate Has skin benefit? +71 more	water Has skin benefit? disodium edta Has skin benefit? +46 more	water Has skin benefit? glycerin Has skin benefit? +37 more	water Has skin benefit? glycerin Has skin benefit? +52 more	water Has skin benefit? cyclopentasiloxane Has skin benefit? +157 more	water Has skin benefit? glycerin Has skin benefit? +83 more	water Has skin benefit? butylene glycol Has skin benefit? +77 more	water Has skin benefit? coco-caprylate/caprate Has skin benefit? +49 more

PRODUCT REVIEW

Darphin Predermine Sculpting Night Cream

Works for:

Can it cause trouble?

Key actives

Cheaper alternatives

Product summary

Ingredient callouts

Irritation risk

Price

What can the product work for?

Works for

Anti-aging

What does the product description say?

Moisturizing

What does the product description say?

Evens skin tone

Honesty check

How honest is this product?

Buy now

US Retailers

UK Retailers

AU Retailers

Can it cause trouble?

Potential irritants

Comodogenic ingredients

User reviews (0)

Similar products & dupes

Ingredients & concentrations

All ingredients

Key Actives

Potential irritants

Comodogenic ingredients

All ingredients

Ingredient list view

Sources