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Product summary

Based on the ingredients included, "111SKIN - Advanced Edit" works well for moisturizing the skin. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (acetyl hexapeptide-8, dextran, glycerin, glycogen and hydrolyzed collagen) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (cholesterol, glycine soja oil, hydrolyzed collagen, ricinus communis seed oil and c10-18 triglycerides) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • this moisturizer contains an effective form of retinoids (vitamin A): retinol 0.15% - 0.60%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of retinoids is that they can be irritating. If you are not already using a retinoid in your routine, it is best to start slowly and apply the retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily. Because of the irritation risk of retinoids, we recommend to have another, retinoid-free moisturizer in your routine to use on the alternative days or when your skin feels dry.
  • We like that this moisturizer contains peptides (trifluoroacetyl tripeptide-2 0.15% - 0.65% and acetyl hexapeptide-8 0.15% - 0.60%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
  • Adenosine 0.15% - 0.70% in this product adds an anti-aging property to it. Adenosine is a chemical present inside our skin cells. A clinical trial confirmed that topical application of adenosine in a low concentration reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where we our mimic is the most active, for example, in the corners of the eyes or on the forehead).
  • In addition, this moisturizer contains Allantoin (0.85% - 1.30%). Allantoin is helpful in wound-healing and can help restore the skin barrier faster. It might also be able to improve scars, but the evidence is not very strong for this.

Irritation risk

There are quite a few common irritants in this product, including ingredients without particular skin benefits. We would not recommend it for sensitive skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 66.00$ in the United States.

For a detailed price comparison: click here.